The anxiety and the responsibility of the rapidly increasing work brought weariness of mind and body, and in March, 1876, Dr. Swain returned to America for a much needed rest. This was extended to the autumn of 1879 when, on September 25, she again sailed for India, arriving in Bombay November 6. At the conference held in Cawnpore in January, 1880, Dr. Swain received her appointment to Bareilly and with gladness of heart took up her old work.