A great door and effectual is opened - Θυοα γαρ μοι ανεωγε μεγαλη και ενεργης· A great and energetic door is opened to me; that is, God has made a grand opening to me in those parts, which I perceive will require much labor; and besides, I shall have many adversaries to oppose me. So Bp. Pearce understands the words ενεργης, not as signifying effectual, but as implying full of labor. Door often signifies occasion or opportunity; but here, the apostle may allude to the throwing open of the great doors of the Circus Maximus before the chariot races began; and the many adversaries may refer to the numerous competitors in those races.

God gave him a grand opportunity to preach the Gospel; but he was not to expect that either Satan or wicked men would leave him unmolested.

a great.

Acts 19:8 And he went into the synagogue, and spoke boldly for the space of three months...

*etc:

door.

Acts 14:27 And when they were come, and had gathered the church together, they rehearsed all that God had done with them...

2 Corinthians 2:12 Furthermore, when I came to Troas to preach Christ's gospel, and a door was opened to me of the Lord,

Colossians 4:3 With praying also for us, that God would open to us a door of utterance, to speak the mystery of Christ, for which I am also in bonds:

Revelation 3:7,8 And to the angel of the church in Philadelphia write; These things said he that is holy, he that is true, he that has the key of David...

there.

1 Corinthians 15:32 If after the manner of men I have fought with beasts at Ephesus, what advantages it me, if the dead rise not? let us eat and drink...

Acts 19:9,10 But when divers were hardened, and believed not, but spoke evil of that way before the multitude, he departed from them...

2 Corinthians 1:8-10 For we would not, brothers, have you ignorant of our trouble which came to us in Asia, that we were pressed out of measure...

Philippians 3:18 (For many walk, of whom I have told you often, and now tell you even weeping, that they are the enemies of the cross of Christ:

The Twenty-Second Psalm.
The Cross of Christ. THE Twenty-second Psalm contains a most remarkable prophecy. The human instrument through whom this prophecy was given is King David. The Psalm does not contain the experience of the King, though he passed through great sufferings, yet the sufferings he speaks of in this Psalm are not his own. They are the sufferings of Christ. It is written in the New Testament that the prophets searched and enquired diligently about the coming salvation. The Spirit of Christ, which was in …
Arno Gaebelein—The Lord of Glory

The Fourth Commandment
Remember the Sabbath-day to keep it holy. Six days shalt thou labour, and do all thy work: but the seventh day is the Sabbath of the Lord thy God; in it thou shalt not do any work, thou, nor thy son, nor thy daughter, thy manservant, nor thy maid-servant, nor thy cattle, nor thy stranger that is within thy gates. For in six days the Lord made heaven and earth, the sea, and all that in them is, and rested the seventh day; wherefore the Lord blessed the Sabbath-day and hallowed it. Exod 20: 8-11. This …
Thomas Watson—The Ten Commandments

Differences in Judgment About Water Baptism, no Bar to Communion: Or, to Communicate with Saints, as Saints, Proved Lawful.
IN ANSWER TO A BOOK WRITTEN BY THE BAPTISTS, AND PUBLISHED BY MR. T. PAUL AND MR. W. KIFFIN, ENTITLED, 'SOME SERIOUS REFLECTIONS ON THAT PART OF MR BUNYAN'S CONFESSION OF FAITH, TOUCHING CHURCH COMMUNION WITH UNBAPTIZED BELIEVERS.' WHEREIN THEIR OBJECTIONS AND ARGUMENTS ARE ANSWERED, AND THE DOCTRINE OF COMMUNION STILL ASSERTED AND VINDICATED. HERE IS ALSO MR. HENRY JESSE'S JUDGMENT IN THE CASE, FULLY DECLARING THE DOCTRINE I HAVE ASSERTED. BY JOHN BUNYAN. 'Should not the multitude of words be answered? …
John Bunyan—The Works of John Bunyan Volumes 1-3