And God went up from him - This was not a vision, nor a strong mental impression, but a real manifestation of God. Jacob saw and heard him speak, and before his eyes he went up - ascended to heaven. This was no doubt the future Savior, the Angel of the covenant. See Genesis 16:7.

Genesis 11:5 And the LORD came down to see the city and the tower, which the children of men built.

Genesis 17:22 And he left off talking with him, and God went up from Abraham.

Genesis 18:33 And the LORD went his way, as soon as he had left communing with Abraham: and Abraham returned to his place.

Judges 6:21 Then the angel of the LORD put forth the end of the staff that was in his hand, and touched the flesh and the unleavened cakes...

Judges 13:20 For it came to pass, when the flame went up toward heaven from off the altar...

Luke 24:31 And their eyes were opened, and they knew him; and he vanished out of their sight.

The Trials and visions of Devout Youth
'And Jacob dwelt in the land wherein his father was a stranger, in the land of Canaan. These are the generations of Jacob. Joseph, being seventeen years old, was feeding the flock with his brethren; and the lad was with the sons of Bilhah, and with the sons of Zilpah, his father's wives: and Joseph brought unto his father their evil report. Now Israel loved Joseph more than all his children, because he was the son of his old age: and he made him a coat of many colours. And when his brethren saw that …
Alexander Maclaren—Expositions of Holy Scripture