Surely he hath borne our griefs, and carried {f} our sorrows: yet we did esteem him {g} stricken, smitten by God, and afflicted.

(f) That is, the punishment due to our sins, for which he has both suffered and made satisfaction, Mt 8:17, 1Pe 2:24.

(g) We judge evil, thinking that he was punished for his own sins, and not for ours.Isaiah 53:4 Parallel Commentaries

The Suffering Servant --vi
'Therefore will I divide Him a portion with the great, and He shall divide the spoil with the strong; because He hath poured out His soul unto death: and was numbered with the transgressors; and He bare the sins of many, and made intercession for the transgressors.'--ISAIAH liii. 12. The first clause of this verse is somewhat difficult. There are two ways of understanding it. One is that adopted in A. V., according to which the suffering Servant is represented as equal to the greatest conquerors. …
Alexander Maclaren—Expositions of Holy Scripture

The Suffering Servant-I
'For He grew up before Him as a tender plant, and as a root out of a dry ground He hath no form nor comeliness; and when we see Him, there is no beauty that we should desire Him. 3. He was despised, and rejected of men, a Man of Sorrows, and acquainted with grief: and as one from whom men hide their face He was despised, and we esteemed Him not.'--ISAIAH liii, 2, 3. To hold fast the fulfilment of this prophecy of the Suffering Servant in Jesus it is not necessary to deny its reference to Israel. …
Alexander Maclaren—Expositions of Holy Scripture

Messiah Suffering and Wounded for Us
Surely He hath borne our griefs, and carried our sorrows: ..... He was wounded for our transgressions, He was bruised for our iniquities: the chastisement of our peace was upon Him; and with His stripes we are healed. W hen our Lord was transfigured, Moses and Elijah appeared in glory and conversed with Him. Had we been informed of the interview only, we should probably have desired to know the subject of their conversation, as we might reasonably suppose it turned upon very interesting and important …
John Newton—Messiah Vol. 1

April the Second "On Him!"
"The Lord hath laid on Him the iniquity of us all." --ISAIAH liii. Let me tell a dream which was given by night to one of my dearest friends. He beheld a stupendous range of glorious sun-lit mountains, with their lower slopes enfolded in white mist. "Lord," he cried, "I pray that I may dwell upon those heights!" "Thou must first descend into the vale," a voice replied. Into the vale he went. And down there he found himself surrounded with all manner of fierce, ugly, loathsome things. As he looked …
John Henry Jowett—My Daily Meditation for the Circling Year

Religion a Weariness to the Natural Man.
"He hath no form nor comeliness; and when we shall see Him, there is no beauty that we should desire Him."--Isaiah liii. 2. "Religion is a weariness;" such is the judgment commonly passed, often avowed, concerning the greatest of blessings which Almighty God has bestowed upon us. And when God gave the blessing, He at the same time foretold that such would be the judgment of the world upon it, even as manifested in the gracious Person of Him whom He sent to give it to us. "He hath no form nor …
John Henry Newman—Parochial and Plain Sermons, Vol. VII

The Crucifixion.
"He was oppressed, and He was afflicted, yet He opened not His mouth; He is brought as a lamb to the slaughter, and as a sheep before her shearers is dumb, so He openeth not His mouth."--Isaiah liii. 7. St. Peter makes it almost a description of a Christian, that he loves Him whom he has not seen; speaking of Christ, he says, "whom having not seen, ye love; in whom, though now ye see Him not, yet believing, ye rejoice with joy unspeakable and full of glory." Again he speaks of "tasting that the …
John Henry Newman—Parochial and Plain Sermons, Vol. VII

Of Justification by Christ
It has been objected by some, who dissent from, nay, I may add, by others also, who actually are friends to the present ecclesiastical establishment, that the ministers of the Church of England preach themselves, and not Christ Jesus the Lord; that they entertain their people with lectures of mere morality, without declaring to them the glad tidings of salvation by Jesus Christ. How well grounded such an objection may be, is not my business to inquire: All I shall say at present to the point is, …
George Whitefield—Selected Sermons of George Whitefield

Expiation
Now, Jesus Christ has been made by God an offering for sin; and oh that to-night we may be able to do in reality what the Jew did in metaphor! May we put our hand upon the head of Christ Jesus; as we see him offered up upon the cross for guilty men, may we know that our sins are transferred to him, and may we be able to cry, in the ecstasy of faith, "Great God, I am clean; through Jesus' blood I am clean." I. In trying now to expound the doctrine of Christ's being an offering for sin, we will begin …
Charles Haddon Spurgeon—Spurgeon's Sermons Volume 10: 1864

Sin Laid on Jesus
I hear no dolorous wailings attending this confession of sin; for the next sentence makes it almost a song. "The Lord hath laid on him the iniquity of us all." It is the most grievous sentence of the three; but it is the most charming and the most full of comfort. Strange is it that where misery was concentrated mercy reigned, and where sorrow reached her climax there it is that a weary soul finds sweetest rest. The Savior bruised is the healing of bruised hearts. I want now to draw the hearts of …
Charles Haddon Spurgeon—Spurgeon's Sermons Volume 12: 1866